Across TCGA cell cohorts, ZNF33A mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF33A-associated genes across cancer lineages are KLRF2, PCDH11Y, and OR5H2. Each is linked with ZNF33A in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF33A-to-partner and partner-to-ZNF33A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF33A→partner) and Y-score (partner→ZNF33A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	KLRF2 →	+0.059	+5.754	<.001	.002	3	2
URINARY_TRACT	PCDH11Y →	+0.016	+5.087	<.001	.004	3	1
CNS	OR5H2 →	+0.071	+5.321	<.001	.005	3	1
CNS	DEFB115 →	+0.263	+6.357	<.001	<.001	3	1
LARGE_INTESTINE	C1orf68 →	+0.013	+4.415	.005	.007	3	1
LARGE_INTESTINE	TMEM235 →	+0.016	+4.467	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

ZNF33A survival (RNA) · tumor vs normal (RNA) · all ZNF33A data types