ZNF337

Across TCGA cell cohorts, ZNF337 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF337-associated genes across cancer lineages are MTRNR2L10, GML, and AWAT2. Each is linked with ZNF337 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF337-to-partner and partner-to-ZNF337 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTRNR2L10 grouped by ZNF337-low versus ZNF337-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF337→partner) and Y-score (partner→ZNF337) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	MTRNR2L10 →	+0.006	+5.196	<.001	.005	3	1
BLOOD_Leukemia	GML →	+0.080	+4.152	<.001	.009	3	1
BLOOD_Leukemia	AWAT2 →	+0.010	+4.705	.004	.003	3	1
BLOOD_Leukemia	RGR →	+0.040	+5.269	<.001	<.001	3	1
BLOOD_Leukemia	OR10P1 →	+0.241	+5.507	<.001	<.001	3	1
BLOOD_Leukemia	OR10Q1 →	+0.027	+4.969	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

MTRNR2L10 by ZNF337 expression — OVARY

Explore this box plot interactively →