Across TCGA pan-cancer cohorts, ZNF337-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated ZNF337-AS1 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher ZNF337-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZNF337-AS1 expression acts as an unfavorable survival marker, although some lineages such as READ and SKCM show a favorable association.

LIHC, KIRC, and KICH are the cancer types where ZNF337-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	DFS	Tertile	All	0.419	0.618	<.001	49	view →
KIRC	DFS	Quartile	III,IV	0.307	0.591	.001	45	view →
KICH	DFS	Quartile	All	0.618	1.000	.004	41	view →
READ	OS	Quartile	All	0.982	0.826	.001	40	view →
STAD	DFS	Median	IV	0.178	0.623	<.001	39	view →
LGG	DFS	Median	All	0.671	0.801	<.001	37	view →
UVM	OS	Median	III,IV	0.348	0.861	.002	34	view →
ACC	DFS	Tertile	All	0.399	0.720	.007	30	view →
KIRP	DFS	Tertile	All	0.535	0.742	.002	27	view →
BLCA	DFS	Tertile	IV	0.160	0.557	.015	18	view →
MESO	DFS	Tertile	IV	0.134	0.427	.023	12	view →
THCA	DFS	Quartile	IV	0.377	0.769	.018	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

Exploration

Same gene, other analysis: ZNF337-AS1 tumor-vs-normal RNA expression · all ZNF337-AS1 data types