ZNF334

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF334 mutation is significantly associated with the total protein of many other genes, with 52 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF334-associated genes across cancer lineages are Caspase-7-cleavedD198, JNK_pT183_Y185, and ATM. Each is linked with ZNF334 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF334-to-partner and partner-to-ZNF334 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF334→partner) and Y-score (partner→ZNF334) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADCaspase-7-cleavedD198 →+1.412+2.824<.001.03433
COADJNK_pT183_Y185 →-0.235-2.313.045.03532
UCECATM →-0.338-1.794.014.02432
UCECcIAP →+0.085+1.524.044.00832
COAD4E-BP1 →+0.245+3.000.013.03532
UCECCyclin-B1 →+0.569+1.473<.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

Exploration