ZNF331

Across TCGA patient cohorts, ZNF331 mutation is significantly associated with the RNA expression of many other genes, with 3,047 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF331-associated genes across cancer lineages are CDCA2, HSPA9, and PSMC3IP. Each is linked with ZNF331 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF331-to-partner and partner-to-ZNF331 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDCA2 grouped by ZNF331-low versus ZNF331-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF331→partner) and Y-score (partner→ZNF331) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDCA2 →	+0.603	+3.721	.004	<.001	3	4
UCEC	HSPA9 →	+0.562	+2.938	<.001	<.001	3	4
UCEC	PSMC3IP →	+0.585	+3.721	<.001	<.001	3	4
SKCM	SUPV3L1 →	+0.300	+2.098	.006	<.001	3	4
HNSC	IER3IP1 →	+0.656	+3.227	.001	.009	3	3
LGG	RNU6-1009P →	+0.583	+5.392	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,047 associations by consensus.

CDCA2 by ZNF331 expression — UCEC

Explore this box plot interactively →