ZNF331

Across TCGA cell cohorts, ZNF331 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF331-associated genes across cancer lineages are CXorf51B, CGB2, and HAND1. Each is linked with ZNF331 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF331-to-partner and partner-to-ZNF331 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CXorf51B grouped by ZNF331-low versus ZNF331-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF331→partner) and Y-score (partner→ZNF331) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	CXorf51B →	+0.133	+4.906	<.001	.006	3	1
LARGE_INTESTINE	CGB2 →	+0.558	+2.436	<.001	.008	3	1
LARGE_INTESTINE	HAND1 →	+1.081	+3.567	<.001	.002	3	1
LARGE_INTESTINE	RASGEF1C →	+0.202	+3.321	.004	.005	3	1
LARGE_INTESTINE	OR2T8 →	+0.148	+2.956	<.001	.004	3	1
LARGE_INTESTINE	ALKBH2 →	+0.954	+3.082	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

CXorf51B by ZNF331 expression — OESOPHAGUS

Explore this box plot interactively →