ZNF330

Across TCGA pan-cancer cohorts, ZNF330 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ZNF330 data layer compared with 23 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher ZNF330 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ZNF330 expression acts as an unfavorable survival marker, although some lineages such as LUAD and UCEC show a favorable association.

LUAD, LSCC, and UCEC are the cancer types where ZNF330 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	All	1.000	0.671	.011	18	view →
LSCC	DFS	Quartile	All	0.280	1.000	.004	18	view →
UCEC	DFS	Median	III,IV	0.900	0.499	.025	16	view →
CCRCC	DFS	Quartile	All	0.324	1.000	.006	10	view →
HNSC	OS	Median	II,III,IV	0.800	0.638	.022	9	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ZNF330–LUAD (DFS)

Open the LUAD breakdown →