ZNF330

Across TCGA patient cohorts, ZNF330 RNA expression is significantly associated with the mutation status of many other genes, with 8,051 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF330-associated genes across cancer lineages are TENM3, AHNAK2, and VPS13D. Each is linked with ZNF330 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF330-to-partner and partner-to-ZNF330 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TENM3 grouped by ZNF330-low versus ZNF330-high in COAD.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF330→partner) and Y-score (partner→ZNF330) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TENM3 →	+1.730	+0.271	<.001	<.001	3	6
STAD	AHNAK2 →	+1.905	+0.320	<.001	<.001	3	5
COAD	VPS13D →	+3.727	+0.335	<.001	<.001	3	5
STAD	FAT1 →	+2.263	+0.400	<.001	<.001	3	5
SKCM	ZFHX3 →	+1.536	+0.292	.003	.003	3	5
COAD	BSN →	+3.834	+0.230	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,051 associations by consensus.

TENM3 by ZNF330 expression — COAD

Explore this box plot interactively →