ZNF330

Across TCGA cell cohorts, ZNF330 mutation is significantly associated with the mutation status of many other genes, with 2,484 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF330-associated genes across cancer lineages are DDHD1, SIX4, and SEC23B. Each is linked with ZNF330 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF330-to-partner and partner-to-ZNF330 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DDHD1 grouped by ZNF330-low versus ZNF330-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF330→partner) and Y-score (partner→ZNF330) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	DDHD1 →	+4.014	+4.969	.008	.008	1	2
BLOOD_Lymphoma	SIX4 →	+4.429	+5.247	.005	.005	1	2
BLOOD_Lymphoma	SEC23B →	+4.429	+5.247	.005	.005	1	2
BLOOD_Lymphoma	PAK5 →	+4.014	+4.969	.008	.008	1	2
BLOOD_Lymphoma	POLA1 →	+4.014	+4.969	.008	.008	1	2
BLOOD_Lymphoma	MYEF2 →	+4.429	+5.247	.005	.005	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,484 associations by consensus.

DDHD1 by ZNF330 expression — BLOOD_Lymphoma

Explore this box plot interactively →