ZNF330

Across TCGA cell cohorts, ZNF330 mutation is significantly associated with the drug of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF330-associated genes across cancer lineages are AT7867, Dinaciclib, and 50869. Each is linked with ZNF330 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF330-to-partner and partner-to-ZNF330 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AT7867 grouped by ZNF330-low versus ZNF330-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF330→partner) and Y-score (partner→ZNF330) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	AT7867 →	+0.549	+2.652	.022	.045	3	1
LARGE_INTESTINE	Dinaciclib →	+0.548	+2.646	.033	.047	2	1
LARGE_INTESTINE	50869 →	+0.509	+2.649	.015	.046	2	1
LARGE_INTESTINE	776928 →	+0.674	+2.649	.033	.046	2	1
LARGE_INTESTINE	Quizartinib →	+0.356	+2.652	.027	.045	2	1
LARGE_INTESTINE	Ara-G →	+0.220	+2.722	.008	.040	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

AT7867 by ZNF330 expression — LARGE_INTESTINE

Explore this box plot interactively →