ZNF329

Across TCGA patient cohorts, ZNF329 mutation is significantly associated with the total protein of many other genes, with 68 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF329-associated genes across cancer lineages are PCNA, PKC-delta_pS664, and TFRC. Each is linked with ZNF329 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF329-to-partner and partner-to-ZNF329 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by ZNF329-low versus ZNF329-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF329→partner) and Y-score (partner→ZNF329) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PCNA →	+0.273	+3.182	.014	.009	3	2
COAD	PKC-delta_pS664 →	-0.202	-3.450	<.001	.005	3	2
COAD	TFRC →	+0.706	+2.347	.003	.019	3	2
COAD	ASNS →	+0.517	+2.330	.003	.020	3	2
UCEC	ATM →	-0.646	-3.000	<.001	<.001	3	2
COAD	Caspase-7-cleavedD198 →	+1.252	+3.186	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 68 associations by consensus.

PCNA by ZNF329 expression — COAD

Explore this box plot interactively →