ZNF329

Across TCGA cell cohorts, ZNF329 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ZNF329-associated genes across cancer lineages are APOL5, OR7G2, and WFDC10A. Each is linked with ZNF329 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF329-to-partner and partner-to-ZNF329 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, APOL5 grouped by ZNF329-low versus ZNF329-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF329→partner) and Y-score (partner→ZNF329) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	APOL5 →	+0.026	+3.415	<.001	.002	3	1
LUNG_NSCLC_LUAD	OR7G2 →	+0.015	+4.302	<.001	<.001	3	1
LUNG_NSCLC_LUAD	WFDC10A →	+0.388	+3.536	<.001	.001	3	1
LUNG_NSCLC_LUAD	KRTAP21-1 →	+0.014	+3.944	<.001	.006	3	1
LUNG_NSCLC_LUAD	CLEC2A →	+0.123	+3.043	<.001	.006	3	1
LUNG_NSCLC_LUAD	DEFB134 →	+0.041	+3.201	.004	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

APOL5 by ZNF329 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →