ZNF326

Across TCGA cell cohorts, ZNF326 mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF326-associated genes across cancer lineages are USP29, S100G, and APOC4. Each is linked with ZNF326 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF326-to-partner and partner-to-ZNF326 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USP29 grouped by ZNF326-low versus ZNF326-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF326→partner) and Y-score (partner→ZNF326) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	USP29 →	+0.007	+3.415	<.001	.001	3	2
CNS	S100G →	+0.203	+4.321	<.001	.009	3	2
LUNG_NSCLC_LUAD	APOC4 →	+0.040	+4.681	<.001	.003	3	2
SKIN	KRTAP5-11 →	+0.035	+5.099	<.001	<.001	3	1
LUNG_SCLC	DEFB126 →	+0.123	+4.817	<.001	.001	3	1
LUNG_SCLC	GH2 →	+0.113	+4.269	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

USP29 by ZNF326 expression — LARGE_INTESTINE

Explore this box plot interactively →