ZNF324B

Across TCGA pan-cancer cohorts, ZNF324B Mutation is linked to patient survival in 11 of 34 cancer types, making it a survival-associated ZNF324B data layer compared with 22 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher ZNF324B Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF324B expression acts as an unfavorable survival marker.

LUAD, HNSC, and LUSC are the cancer types where ZNF324B Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.200	0.815	<.001	42	view →
HNSC	OS	Median	II,III,IV	0.075	0.756	<.001	36	view →
LUSC	OS	Median	III,IV	0.072	0.691	<.001	32	view →
UCS	OS	Median	All	0.007	0.689	<.001	24	view →
LIHC	OS	Median	All	0.028	0.777	<.001	24	view →
COAD	DFS	Median	All	0.150	0.692	<.001	24	view →
MESO	DFS	Median	III,IV	0.082	0.414	.007	18	view →
STAD	DFS	Median	II,III,IV	0.159	0.537	.013	17	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
SARC	OS	Median	All	0.238	0.826	.001	3	view →
ACC	DFS	Median	All	0.195	0.748	.003	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

ZNF324B–LUAD (OS)

Open the LUAD breakdown →