ZNF324

Across TCGA cell cohorts, ZNF324 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF324-associated genes across cancer lineages are ZAN, DEFA4, and UTF1. Each is linked with ZNF324 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF324-to-partner and partner-to-ZNF324 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZAN grouped by ZNF324-low versus ZNF324-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF324→partner) and Y-score (partner→ZNF324) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	ZAN →	+0.005	+4.087	<.001	.009	3	1
LARGE_INTESTINE	DEFA4 →	+0.022	+3.700	<.001	.009	3	1
LARGE_INTESTINE	UTF1 →	+0.012	+3.217	.001	.006	3	1
LARGE_INTESTINE	BPIFA1 →	+0.114	+3.103	.003	.004	3	1
BLOOD_Leukemia	INSL5 →	+0.040	+3.339	.001	.006	3	1
BLOOD_Leukemia	SELENOV →	+0.063	+3.339	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

ZAN by ZNF324 expression — URINARY_TRACT

Explore this box plot interactively →