ZNF322

Across TCGA patient cohorts, ZNF322 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,977 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF322-associated proteins across cancer lineages are HDAC2, IRF2BP1, and MLKL. Each is linked with ZNF322 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF322-to-partner and partner-to-ZNF322 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF322 versus HDAC2 in LSCC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF322→partner) and Y-score (partner→ZNF322) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	HDAC2 →	+0.302	+0.930	<.001	<.001	3	5
HNSC	IRF2BP1 →	+0.348	+0.704	<.001	<.001	3	5
BRCA	MLKL →	-0.491	-0.523	<.001	<.001	3	5
GBM	GNL1 →	+0.257	+0.363	<.001	<.001	3	5
HNSC	RAD21 →	+0.187	+0.689	.001	<.001	3	4
GBM	PLCG2 →	-0.425	-0.277	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,977 associations by consensus.

ZNF322 vs HDAC2 — LSCC

Explore this scatter interactively →