ZNF322

Across TCGA cell cohorts, ZNF322 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF322-associated genes across cancer lineages are BPIFB6, SEBOX, and INSRR. Each is linked with ZNF322 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF322-to-partner and partner-to-ZNF322 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BPIFB6 grouped by ZNF322-low versus ZNF322-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF322→partner) and Y-score (partner→ZNF322) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BPIFB6 →	+0.020	+4.437	<.001	.004	3	1
LARGE_INTESTINE	SEBOX →	+0.061	+3.793	<.001	.007	3	1
LARGE_INTESTINE	INSRR →	+0.039	+4.584	<.001	.003	3	1
LARGE_INTESTINE	ADAM7 →	+0.005	+3.930	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

BPIFB6 by ZNF322 expression — LARGE_INTESTINE

Explore this box plot interactively →