zinc finger protein 321, pseudogeneGenealiases: []
Q-omics provides the consensus-scored ZNF321P profile across patient tissues and cancer cell-line models. ZNF321P expression is associated with patient survival in 25 of 34 cancer types, with the highest sampling consensus in BLCA. Among the 18 cancer types available for tumor–normal comparison, ZNF321P is differentially expressed in 6, with the highest sampling consensus in KICH. Additionally, ZNF321P RNA expression shows 20,175 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight BLCA, KICH, and ACC as cancer lineages where ZNF321P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for ZNF321P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes ZNF321P survival associations across molecular data types. ZNF321P RNA expression shows survival associations in the most cancer types (25). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible ZNF321P RNA expression–survival associations across cancer types. High ZNF321P expression shows unfavorable associations in LIHC and LGG, but favorable associations in BLCA, UCS, CHOL and THYM. The BLCA Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify BLCA as the clearest survival context for ZNF321P RNA expression.
This table summarizes ZNF321P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 6. The strongest signals are observed in KICH for RNA.
This table ranks reproducible tumor–normal expression differences for ZNF321P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. ZNF321P shows lower tumor expression in KICH and THCA and higher tumor expression in STAD, LIHC, CHOL and PAAD. The KICH box plot shows higher ZNF321P RNA expression in normal versus tumor tissue (log2 FC = −1.343, t-test p < 0.001).
This table shows molecular features associated with ZNF321P in patient tissues and cancer cell lines. In patient samples, ZNF321P shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set.