ZNF32

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF32 mutation is significantly associated with the RNA expression of many other genes, with 1,428 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF32-associated genes across cancer lineages are SPINT4, RNU6ATAC9P, and PSMA6P3. Each is linked with ZNF32 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF32-to-partner and partner-to-ZNF32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPINT4 grouped by ZNF32-low versus ZNF32-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF32→partner) and Y-score (partner→ZNF32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMSPINT4 →+0.073+3.622<.001.00532
SKCMRNU6ATAC9P →+0.232+3.454<.001.00632
LUSCPSMA6P3 →+0.368+4.984<.001.00932
UCECRN7SL454P →+0.185+2.060<.001.00432
UCECRNA5SP422 →+0.642+1.893.001.00832
UCECRNA5SP420 →+0.590+2.189<.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,428 associations by consensus.

SPINT4 by ZNF32 expression — SKCM

Box plot of SPINT4 in ZNF32-low vs ZNF32-high samples in SKCM.

Explore this box plot interactively →

Exploration