ZNF32

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZNF32 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ZNF32-associated genes across cancer lineages are UCMA, ELOA3DP, and BPIFA1. Each is linked with ZNF32 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF32-to-partner and partner-to-ZNF32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UCMA grouped by ZNF32-low versus ZNF32-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF32→partner) and Y-score (partner→ZNF32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEUCMA →+0.028+5.217<.001<.00131
LARGE_INTESTINEELOA3DP →+0.044+4.273<.001.00631
LARGE_INTESTINEBPIFA1 →+0.186+4.273<.001.00631
LUNG_NSCLC_LUADMS4A13 →+0.325+5.228<.001.00531
LUNG_NSCLC_LUADOR4C12 →+0.022+5.662<.001.00231
LUNG_NSCLC_LUADOR4M2 →+0.267+4.887<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

UCMA by ZNF32 expression — LARGE_INTESTINE

Box plot of UCMA in ZNF32-low vs ZNF32-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration