ZNF318

Across TCGA patient cohorts, ZNF318 mutation is significantly associated with the RNA expression of many other genes, with 4,918 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF318-associated genes across cancer lineages are LRR1, GPATCH3, and USP15. Each is linked with ZNF318 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF318-to-partner and partner-to-ZNF318 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LRR1 grouped by ZNF318-low versus ZNF318-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF318→partner) and Y-score (partner→ZNF318) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LRR1 →	+0.497	+1.784	<.001	<.001	3	5
UCEC	GPATCH3 →	+0.251	+2.345	.006	<.001	3	4
HNSC	USP15 →	+0.452	+3.391	.003	.004	3	4
UCEC	TIMM44 →	+0.412	+2.032	<.001	<.001	3	4
LUAD	ZNF526 →	+0.432	+2.620	<.001	.005	3	4
BLCA	HOXC6 →	+0.854	+2.229	.004	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,918 associations by consensus.

LRR1 by ZNF318 expression — UCEC

Explore this box plot interactively →