ZNF318

Across TCGA patient cohorts, ZNF318 mutation is significantly associated with the total protein of many other genes, with 52 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF318-associated genes across cancer lineages are Myosin-IIa_pS1943, ATM, and ASNS. Each is linked with ZNF318 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF318-to-partner and partner-to-ZNF318 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Myosin-IIa_pS1943 grouped by ZNF318-low versus ZNF318-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF318→partner) and Y-score (partner→ZNF318) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Myosin-IIa_pS1943 →	+0.354	+2.347	.025	.019	3	4
COAD	ATM →	-0.550	-2.313	.001	.035	3	3
COAD	ASNS →	+0.369	+3.000	.038	.035	3	3
LUAD	PDCD4 →	-0.472	-3.442	.019	.005	3	2
UCEC	14-3-3_beta →	-0.069	-1.388	.021	.041	3	2
UCEC	MEK1 →	+0.361	+2.459	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 52 associations by consensus.

Myosin-IIa_pS1943 by ZNF318 expression — COAD

Explore this box plot interactively →