ZNF318

Across TCGA cell cohorts, ZNF318 mutation is significantly associated with the RNA expression of many other genes, with 884 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF318-associated genes across cancer lineages are KRT37, IQCC, and DEFB108B. Each is linked with ZNF318 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF318-to-partner and partner-to-ZNF318 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRT37 grouped by ZNF318-low versus ZNF318-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF318→partner) and Y-score (partner→ZNF318) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	KRT37 →	+0.030	+4.584	<.001	.001	3	2
BLOOD_Leukemia	IQCC →	+0.543	+3.489	.006	.001	3	2
BLOOD_Leukemia	DEFB108B →	+0.053	+2.684	.008	.004	3	2
BLOOD_Leukemia	FKBPL →	+0.646	+3.215	.001	.005	3	2
STOMACH	CT47B1 →	+0.028	+4.129	.008	.007	3	2
LARGE_INTESTINE	ZBED4 →	+0.520	+2.596	.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 884 associations by consensus.

KRT37 by ZNF318 expression — CNS

Explore this box plot interactively →