ZNF302

Across TCGA patient cohorts, ZNF302 mutation is significantly associated with the total protein of many other genes, with 43 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF302-associated genes across cancer lineages are 14-3-3_beta, A-Raf_pS299, and GAPDH. Each is linked with ZNF302 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF302-to-partner and partner-to-ZNF302 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 14-3-3_beta grouped by ZNF302-low versus ZNF302-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF302→partner) and Y-score (partner→ZNF302) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.114	-2.780	.001	.003	3	1
UCEC	A-Raf_pS299 →	-0.213	-2.459	<.001	<.001	3	1
UCEC	GAPDH →	+0.393	+1.700	.035	.042	3	1
UCEC	Heregulin →	-0.171	-2.893	<.001	.001	3	1
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.425	+1.817	.015	.015	3	1
UCEC	INPP4B →	-0.276	-2.700	.013	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

14-3-3_beta by ZNF302 expression — UCEC

Explore this box plot interactively →