ZNF302

Across TCGA cell cohorts, ZNF302 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF302-associated genes across cancer lineages are TMEM114, SCGB3A2, and STOML3. Each is linked with ZNF302 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF302-to-partner and partner-to-ZNF302 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMEM114 grouped by ZNF302-low versus ZNF302-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF302→partner) and Y-score (partner→ZNF302) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	TMEM114 →	+0.068	+4.867	<.001	.009	3	2
LARGE_INTESTINE	SCGB3A2 →	+0.253	+3.510	.009	.003	3	2
BLOOD_Lymphoma	STOML3 →	+0.006	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	SPANXN4 →	+0.110	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	BPIFA1 →	+1.002	+5.643	<.001	.002	3	1
SKIN	OR1L3 →	+0.029	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

TMEM114 by ZNF302 expression — BLOOD_Lymphoma

Explore this box plot interactively →