ZNF300

Across TCGA patient cohorts, ZNF300 protein abundance is significantly associated with the protein abundance of many other proteins, with 817 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF300-associated proteins across cancer lineages are WDR20_S357, ZC3H13_S198, and ZC3H13_S207. Each is linked with ZNF300 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF300-to-partner and partner-to-ZNF300 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF300 versus WDR20_S357 in UCEC, with a Pearson correlation of -0.86.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF300→partner) and Y-score (partner→ZNF300) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	WDR20_S357 →	-1.657	-3.679	<.001	<.001	3	1
UCEC	ZC3H13_S198 →	-1.175	-3.377	<.001	<.001	3	1
UCEC	ZC3H13_S207 →	+0.391	+2.574	.001	.001	3	1
UCEC	ZKSCAN8_S12 →	-0.691	-2.574	<.001	.001	3	1
UCEC	RICTOR_T1135 →	-0.898	-2.574	<.001	.001	3	1
UCEC	RPA3 →	-0.614	-2.575	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 817 associations by consensus.

ZNF300 vs WDR20_S357 — UCEC

Explore this scatter interactively →