ZNF300

Across TCGA patient cohorts, ZNF300 protein abundance is significantly associated with the go_rna of many other GO terms, with 118 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF300-associated GO terms across cancer lineages are Nucleoside triphosphate metabolic process, Transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery, and Positive regulation of cholesterol efflux. Each is linked with ZNF300 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF300-to-partner and partner-to-ZNF300 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleoside triphosphate metabolic process grouped by ZNF300-low versus ZNF300-high in UCEC.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF300→partner) and Y-score (partner→ZNF300) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Nucleoside triphosphate metabolic process →	+0.055	+3.090	.002	<.001	3	1
UCEC	Transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery →	+0.111	+2.338	.004	.008	3	1
UCEC	Positive regulation of cholesterol efflux →	+0.103	+2.568	.008	.002	3	1
UCEC	Response to acid chemical →	+0.080	+2.994	.002	.001	3	1
UCEC	Proton motive force-driven ATP synthesis →	+0.088	+2.568	.006	.002	3	1
UCEC	Nucleoside phosphate biosynthetic process →	+0.056	+2.575	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 118 associations by consensus.

Nucleoside triphosphate metabolic process by ZNF300 expression — UCEC

Explore this box plot interactively →