ZNF300

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZNF300 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,064 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ZNF300-associated GO terms across cancer lineages are Regulation of chromosome organization, Protein localization to nucleus, and Nuclear export. Each is linked with ZNF300 in more than 7 cancer types. Because this analysis shows association rather than direction, both ZNF300-to-partner and partner-to-ZNF300 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of chromosome organization grouped by ZNF300-low versus ZNF300-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF300→partner) and Y-score (partner→ZNF300) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINRegulation of chromosome organization →+0.063+1.185.002.00138
LUNG_SCLCProtein localization to nucleus →+0.047+1.103<.001.00538
PANCREASNuclear export →+0.061+1.484<.001<.00138
PANCREASProteasomal ubiquitin-independent protein catabolic process →+0.080+1.518.001<.00137
OVARYPositive regulation of cytoplasmic translation →+0.108+1.447<.001.00137
STOMACHRegulation of RNA export from nucleus →+0.150+2.142<.001.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,064 associations by consensus.

Regulation of chromosome organization by ZNF300 expression — SKIN

Box plot of Regulation of chromosome organization in ZNF300-low vs ZNF300-high samples in SKIN.

Explore this box plot interactively →

Exploration