ZNF30-AS1

Across TCGA pan-cancer cohorts, ZNF30-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated ZNF30-AS1 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher ZNF30-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ZNF30-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and UVM show a favorable association.

UCS, UVM, and COAD are the cancer types where ZNF30-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Median	III,IV	0.531	0.134	<.001	120	view →
UVM	OS	Median	All	0.840	0.408	<.001	96	view →
COAD	OS	Median	All	0.805	0.927	<.001	32	view →
KIRP	DFS	Median	IV	0.039	0.623	.001	30	view →
BLCA	OS	Tertile	All	0.781	0.663	.007	24	view →
DLBC	DFS	Tertile	All	0.495	0.866	.012	18	view →
BRCA	OS	Quartile	III,IV	0.970	0.838	.002	12	view →
KIRC	OS	Tertile	All	0.894	0.825	.006	11	view →
LUSC	DFS	Median	All	0.305	0.451	.001	10	view →
UCEC	DFS	Tertile	All	0.786	0.863	.008	10	view →
LAML	DFS	Median	All	0.504	0.288	.015	10	view →
LUAD	DFS	Tertile	All	0.866	0.730	.012	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

ZNF30-AS1–UCS (DFS)

Open the UCS breakdown →