ZNF3

Across TCGA patient cohorts, ZNF3 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,657 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF3-associated proteins across cancer lineages are ZKSCAN1, MEPCE, and GTF2I. Each is linked with ZNF3 in more than 8 cancer types. Because this analysis shows association rather than direction, both ZNF3-to-partner and partner-to-ZNF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF3 versus ZKSCAN1 in LSCC, with a Pearson correlation of 0.75.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF3→partner) and Y-score (partner→ZNF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ZKSCAN1 →	+0.424	+0.682	<.001	<.001	3	9
LSCC	MEPCE →	+0.406	+0.676	<.001	<.001	3	8
HNSC	GTF2I →	+0.524	+0.873	<.001	<.001	3	8
GBM	ADNP →	+0.410	+0.373	<.001	<.001	3	7
OV	GIGYF1 →	+0.308	+0.453	<.001	<.001	3	7
GBM	PTPRC →	-0.688	-0.361	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,657 associations by consensus.

ZNF3 vs ZKSCAN1 — LSCC

Explore this scatter interactively →