ZNF296

Across TCGA patient cohorts, ZNF296 mutation is significantly associated with the RNA expression of many other genes, with 756 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF296-associated genes across cancer lineages are RNU6-831P, MIR7150, and RNA5SP408. Each is linked with ZNF296 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF296-to-partner and partner-to-ZNF296 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-831P grouped by ZNF296-low versus ZNF296-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF296→partner) and Y-score (partner→ZNF296) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-831P →	+0.133	+3.990	<.001	.009	3	3
BLCA	MIR7150 →	+0.198	+4.147	.001	.009	3	2
UCEC	RNA5SP408 →	+0.451	+3.186	<.001	.002	3	2
LUSC	VN1R91P →	+0.120	+4.309	<.001	.007	3	2
HNSC	MIR449B →	+0.323	+7.954	<.001	.008	3	2
UCEC	MIR3193 →	+0.640	+2.352	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 756 associations by consensus.

RNU6-831P by ZNF296 expression — SKCM

Explore this box plot interactively →