ZNF296

Across TCGA patient cohorts, ZNF296 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF296-associated genes across cancer lineages are PDCD4, Rab11, and PCNA. Each is linked with ZNF296 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF296-to-partner and partner-to-ZNF296 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDCD4 grouped by ZNF296-low versus ZNF296-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF296→partner) and Y-score (partner→ZNF296) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCD4 →	-0.610	-3.169	.018	.020	3	1
UCEC	Rab11 →	-0.189	-3.169	.017	.020	3	1
UCEC	PCNA →	+0.342	+3.169	.003	.020	2	1
UCEC	TFRC →	+0.664	+3.169	.022	.020	2	1
UCEC	Caspase-8 →	-0.296	-3.169	.031	.020	2	1
UCEC	C-Raf →	+0.250	+3.169	.001	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

PDCD4 by ZNF296 expression — UCEC

Explore this box plot interactively →