ZNF285

Across TCGA patient cohorts, ZNF285 mutation is significantly associated with the RNA expression of many other genes, with 2,187 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF285-associated genes across cancer lineages are RNA5SP417, PRAMEF36P, and TERF1P6. Each is linked with ZNF285 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF285-to-partner and partner-to-ZNF285 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP417 grouped by ZNF285-low versus ZNF285-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF285→partner) and Y-score (partner→ZNF285) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP417 →	+0.486	+2.181	<.001	.001	3	3
LUSC	PRAMEF36P →	+0.014	+5.333	<.001	.001	3	3
BRCA	TERF1P6 →	+0.093	+5.463	<.001	<.001	3	2
UCEC	MEX3D →	+0.586	+3.721	.001	<.001	3	2
UCEC	NELFB →	+0.429	+2.459	.001	<.001	3	2
UCEC	WDR5 →	+0.366	+2.095	.007	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,187 associations by consensus.

RNA5SP417 by ZNF285 expression — UCEC

Explore this box plot interactively →