ZNF285

Across TCGA cell cohorts, ZNF285 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,425 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF285-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Vesicle coating. Each is linked with ZNF285 in more than 7 cancer types. Because this analysis shows association rather than direction, both ZNF285-to-partner and partner-to-ZNF285 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by ZNF285-low versus ZNF285-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF285→partner) and Y-score (partner→ZNF285) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Negative regulation of myoblast fusion →	+0.103	+0.932	<.001	<.001	3	8
SKIN	Negative regulation of syncytium formation by plasma membrane fusion →	+0.103	+0.939	<.001	<.001	3	8
PANCREAS	Vesicle coating →	+0.070	+0.802	<.001	<.001	3	8
URINARY_TRACT	Golgi organization →	+0.043	+0.932	.001	<.001	3	7
BLOOD_Myeloma	Positive regulation of telomere maintenance →	+0.061	+1.064	.004	.006	3	7
BLOOD_Lymphoma	Striated muscle contraction →	+0.048	+0.496	<.001	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,425 associations by consensus.

Negative regulation of myoblast fusion by ZNF285 expression — SKIN

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