Across TCGA cell cohorts, ZNF284 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible ZNF284-associated genes across cancer lineages are MYOD1, XAGE3, and OR10W1. Each is linked with ZNF284 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF284-to-partner and partner-to-ZNF284 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF284→partner) and Y-score (partner→ZNF284) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	MYOD1 →	+0.025	+4.922	<.001	.009	3	2
OESOPHAGUS	XAGE3 →	+0.163	+4.906	<.001	.006	3	1
LARGE_INTESTINE	OR10W1 →	+0.022	+4.977	<.001	.007	3	1
LARGE_INTESTINE	SLC15A5 →	+0.023	+5.415	<.001	.004	3	1
LARGE_INTESTINE	OR10G2 →	+0.074	+4.977	<.001	.007	3	1
LUNG_SCLC	GH2 →	+0.105	+4.269	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

ZNF284 survival (RNA) · tumor vs normal (RNA) · all ZNF284 data types