ZNF282

Across TCGA patient cohorts, ZNF282 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,895 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF282-associated proteins across cancer lineages are SSBP1, FMNL1_S1031, and GTF2I. Each is linked with ZNF282 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZNF282-to-partner and partner-to-ZNF282 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF282 versus SSBP1 in LSCC, with a Pearson correlation of 0.55.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF282→partner) and Y-score (partner→ZNF282) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SSBP1 →	+0.466	+0.592	<.001	<.001	3	7
LSCC	FMNL1_S1031 →	-0.698	-0.577	<.001	<.001	3	5
GBM	GTF2I →	+0.467	+0.406	<.001	<.001	3	5
GBM	PTPRC →	-0.514	-0.254	<.001	<.001	3	5
GBM	VSIR →	-0.537	-0.265	<.001	.009	3	5
GBM	ZC3HC1 →	+0.206	+0.328	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,895 associations by consensus.

ZNF282 vs SSBP1 — LSCC

Explore this scatter interactively →