ZNF282

Across TCGA patient cohorts, ZNF282 protein abundance is significantly associated with the RNA expression of many other genes, with 1,968 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ZNF282-associated genes across cancer lineages are PMM1, DOK5, and CREB3L4. Each is linked with ZNF282 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF282-to-partner and partner-to-ZNF282 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF282 versus PMM1 in UCEC, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF282→partner) and Y-score (partner→ZNF282) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PMM1 →	+0.737	+0.409	.002	.004	3	2
HNSC	DOK5 →	-0.922	-0.471	.001	.001	2	3
UCEC	CREB3L4 →	+1.130	+0.422	.004	.005	3	2
UCEC	C6orf132 →	-0.875	-0.480	<.001	<.001	3	2
LSCC	RPL32P33 →	-0.429	-0.461	.001	.005	3	2
CCRCC	CTDSPL →	-0.695	-0.310	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,968 associations by consensus.

ZNF282 vs PMM1 — UCEC

Explore this scatter interactively →