ZNF282

Across TCGA patient cohorts, ZNF282 protein abundance is significantly associated with the protein abundance of many other proteins, with 6,177 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ZNF282-associated proteins across cancer lineages are ZNF318_S464, ZNF608_S1430, and ZNF644_T1020. Each is linked with ZNF282 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF282-to-partner and partner-to-ZNF282 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF282 versus ZNF318_S464 in BRCA, with a Pearson correlation of 0.47.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF282→partner) and Y-score (partner→ZNF282) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ZNF318_S464 →	+0.970	+0.896	<.001	<.001	3	2
BRCA	ZNF608_S1430 →	+1.186	+0.670	.001	<.001	3	2
BRCA	ZNF644_T1020 →	+1.850	+0.615	<.001	.001	3	2
BRCA	ZNF696_S86 →	+1.896	+0.992	<.001	<.001	3	2
BRCA	ATP5MPL →	+0.936	+0.702	<.001	<.001	3	2
BRCA	BAZ1B_S312 →	+1.270	+0.600	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,177 associations by consensus.

ZNF282 vs ZNF318_S464 — BRCA

Explore this scatter interactively →