ZNF280A

Across TCGA cell cohorts, ZNF280A RNA expression is significantly associated with the go_rna of many other GO terms, with 1,587 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ZNF280A-associated GO terms across cancer lineages are Protein folding, Porphyrin-containing compound metabolic process, and Cholesterol transport. Each is linked with ZNF280A in more than 7 cancer types. Because this analysis shows association rather than direction, both ZNF280A-to-partner and partner-to-ZNF280A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein folding grouped by ZNF280A-low versus ZNF280A-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF280A→partner) and Y-score (partner→ZNF280A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Protein folding →	+0.056	+0.562	.001	.006	3	8
LUNG_SCLC	Porphyrin-containing compound metabolic process →	+0.060	+0.415	.005	.008	3	6
SKIN	Cholesterol transport →	+0.072	+1.097	.003	.001	3	5
OESOPHAGUS	Mitochondrial electron transport, ubiquinol to cytochrome c →	+0.106	+0.681	<.001	.005	3	5
SKIN	Translational initiation →	+0.077	+0.910	<.001	<.001	2	6
SKIN	Potassium ion transport →	-0.050	-1.014	.001	.004	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,587 associations by consensus.

Protein folding by ZNF280A expression — LUNG_SCLC

Explore this box plot interactively →