Across TCGA patient cohorts, ZNF28 mutation is significantly associated with the RNA expression of many other genes, with 3,266 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF28-associated genes across cancer lineages are GOT1, PSMC3IP, and DVL2. Each is linked with ZNF28 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF28-to-partner and partner-to-ZNF28 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF28→partner) and Y-score (partner→ZNF28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	GOT1 →	+0.569	+3.424	<.001	<.001	3	4
UCEC	PSMC3IP →	+0.590	+2.159	<.001	<.001	3	4
SKCM	DVL2 →	+0.482	+2.254	<.001	.001	3	4
UCEC	PRIM1 →	+0.522	+1.465	.001	.003	3	4
UCEC	BUB3 →	+0.460	+1.882	<.001	.001	3	4
UCEC	CHAF1A →	+0.648	+2.566	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,266 associations by consensus.

Exploration

ZNF28 survival (RNA) · tumor vs normal (RNA) · all ZNF28 data types