Across TCGA cell cohorts, ZNF28 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,447 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF28-associated GO terms across cancer lineages are DNA integrity checkpoint signaling, Transcription initiation at RNA polymerase II promoter, and Transcription elongation by RNA polymerase II. Each is linked with ZNF28 in more than 7 cancer types. Because this analysis shows association rather than direction, both ZNF28-to-partner and partner-to-ZNF28 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF28→partner) and Y-score (partner→ZNF28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	DNA integrity checkpoint signaling →	+0.050	+0.816	<.001	<.001	3	8
BLOOD_Lymphoma	Transcription initiation at RNA polymerase II promoter →	+0.050	+1.692	<.001	<.001	3	8
BLOOD_Leukemia	Transcription elongation by RNA polymerase II →	+0.063	+1.089	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Sex-chromosome dosage compensation →	+0.077	+1.593	.004	.002	3	7
BLOOD_Leukemia	Negative regulation of calcium ion export across plasma membrane →	+0.043	+0.742	<.001	.002	3	7
BLOOD_Leukemia	Positive regulation of cell division →	+0.062	+0.684	<.001	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,447 associations by consensus.

Exploration

ZNF28 survival (RNA) · tumor vs normal (RNA) · all ZNF28 data types