Across TCGA cell cohorts, ZNF28 mutation is significantly associated with the mutation status of many other genes, with 2,884 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF28-associated genes across cancer lineages are CEP170, ERCC6L2, and CUX1. Each is linked with ZNF28 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF28-to-partner and partner-to-ZNF28 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF28→partner) and Y-score (partner→ZNF28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CEP170 →	+3.823	+4.430	.001	.001	1	5
SKIN	ERCC6L2 →	+3.133	+3.000	.003	.003	1	4
BLOOD_Lymphoma	CUX1 →	+3.162	+4.016	.001	.001	1	4
BLOOD_Leukemia	PRR14L →	+3.338	+4.083	.003	.003	1	4
CNS	OR13C4 →	+5.347	+4.199	<.001	<.001	1	4
BLOOD_Lymphoma	TRANK1 →	+3.162	+4.016	.001	.001	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,884 associations by consensus.

Exploration

ZNF28 survival (RNA) · tumor vs normal (RNA) · all ZNF28 data types