Across TCGA patient cohorts, ZNF277 protein abundance is significantly associated with the RNA expression of many other genes, with 4,202 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF277-associated genes across cancer lineages are ORC5, ZSCAN25, and ZNF85. Each is linked with ZNF277 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF277-to-partner and partner-to-ZNF277 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF277→partner) and Y-score (partner→ZNF277) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ORC5 →	+0.394	+0.212	<.001	.001	3	3
LSCC	ZSCAN25 →	+0.364	+0.265	.002	.004	3	3
HNSC	ZNF85 →	-0.875	-0.257	.003	.004	3	2
LUAD	ASPA →	-0.471	-0.192	.001	.003	3	2
BRCA	AKAP8L →	-0.471	-0.293	.002	.004	3	2
CCRCC	NRL →	-0.417	-0.515	.003	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,202 associations by consensus.

Exploration

ZNF277 survival (RNA) · tumor vs normal (RNA) · all ZNF277 data types