ZNF277

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF277 mutation is significantly associated with the RNA expression of many other genes, with 3,748 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF277-associated genes across cancer lineages are RNF19BPY, FRG2GP, and OR4F21. Each is linked with ZNF277 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF277-to-partner and partner-to-ZNF277 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF277→partner) and Y-score (partner→ZNF277) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCARNF19BPY →+0.016+8.057<.001.00532
LUADFRG2GP →+0.133+4.399.001.00832
BLCAOR4F21 →+0.028+3.899<.001.00232
SKCMTRBV22OR9-2 →+0.087+4.186<.001.00732
UCECPPP6R2 →+0.382+2.413<.001<.00132
UCECNDUFAF5 →+0.310+2.467.002<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,748 associations by consensus.

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