ZNF277

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZNF277 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,697 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF277-associated GO terms across cancer lineages are Leading strand elongation, tRNA dihydrouridine synthesis, and Spliceosome conformational change to release U4 (or U4atac) and U1 (or U11). Each is linked with ZNF277 in more than 10 cancer types. Because this analysis shows association rather than direction, both ZNF277-to-partner and partner-to-ZNF277 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF277→partner) and Y-score (partner→ZNF277) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OESOPHAGUSLeading strand elongation →-0.163-1.547<.001.002311
UPPER_AERODIGESTIVE_TRACTtRNA dihydrouridine synthesis →+0.121+0.684<.001<.001310
STOMACHSpliceosome conformational change to release U4 (or U4atac) and U1 (or U11) →-0.126-1.334.001<.001310
UPPER_AERODIGESTIVE_TRACTNegative regulation of inflammasome-mediated signaling pathway →-0.122-0.818.001<.00139
LUNG_SCLCRegulation of membrane tubulation →+0.131+0.727.001<.00139
OVARYRegulation of telomeric D-loop disassembly →+0.092+0.684<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,697 associations by consensus.

Exploration