ZNF276

Across TCGA patient cohorts, ZNF276 protein abundance is significantly associated with the RNA expression of many other genes, with 9,441 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF276-associated genes across cancer lineages are MAP4K1, RASAL3, and PIK3CG. Each is linked with ZNF276 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF276-to-partner and partner-to-ZNF276 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF276 versus MAP4K1 in HNSC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF276→partner) and Y-score (partner→ZNF276) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MAP4K1 →	+0.896	+0.340	<.001	.001	3	5
HNSC	RASAL3 →	+0.886	+0.316	<.001	<.001	3	5
HNSC	PIK3CG →	+1.145	+0.483	<.001	<.001	3	5
LSCC	RIPOR2 →	+0.870	+0.303	<.001	<.001	3	5
HNSC	GZMK →	+1.442	+0.401	<.001	<.001	3	5
HNSC	ITK →	+1.124	+0.355	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,441 associations by consensus.

ZNF276 vs MAP4K1 — HNSC

Explore this scatter interactively →