ZNF276

Across TCGA patient cohorts, ZNF276 mutation is significantly associated with the RNA expression of many other genes, with 1,692 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF276-associated genes across cancer lineages are ALDH7A1P2, SNRPGP7, and OR5B10P. Each is linked with ZNF276 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF276-to-partner and partner-to-ZNF276 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ALDH7A1P2 grouped by ZNF276-low versus ZNF276-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF276→partner) and Y-score (partner→ZNF276) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ALDH7A1P2 →	+0.084	+5.578	<.001	.004	3	2
HNSC	SNRPGP7 →	+0.372	+5.736	<.001	.003	3	2
HNSC	OR5B10P →	+0.144	+6.763	<.001	<.001	3	2
LGG	RNU6-1009P →	+0.329	+5.392	<.001	.005	3	2
UCEC	BTBD6 →	+0.442	+3.823	.001	<.001	3	2
UCEC	BICD2 →	+0.654	+2.415	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,692 associations by consensus.

ALDH7A1P2 by ZNF276 expression — HNSC

Explore this box plot interactively →