ZNF275

Across TCGA patient cohorts, ZNF275 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,386 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ZNF275-associated proteins across cancer lineages are PARP1, PHF6, and LTBP2. Each is linked with ZNF275 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF275-to-partner and partner-to-ZNF275 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF275 versus PARP1 in HNSC, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF275→partner) and Y-score (partner→ZNF275) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PARP1 →	+0.422	+0.485	<.001	<.001	3	5
HNSC	PHF6 →	+0.365	+0.789	<.001	<.001	3	5
CCRCC	LTBP2 →	+0.635	+0.232	.001	.001	3	4
HNSC	ZNF280C →	+0.340	+0.446	<.001	.001	3	4
LSCC	VPS9D1_S116 →	-0.596	-0.368	.005	.005	3	4
HNSC	TCEAL1 →	+0.407	+0.588	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,386 associations by consensus.

ZNF275 vs PARP1 — HNSC

Explore this scatter interactively →