ZNF275

Across TCGA patient cohorts, ZNF275 protein abundance is significantly associated with the RNA expression of many other genes, with 1,442 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF275-associated genes across cancer lineages are PIGF, EGFLAM, and PLEKHF1. Each is linked with ZNF275 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF275-to-partner and partner-to-ZNF275 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF275 versus PIGF in LUAD, with a Pearson correlation of -0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF275→partner) and Y-score (partner→ZNF275) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PIGF →	-0.530	-0.628	<.001	<.001	3	2
BRCA	EGFLAM →	+0.661	+0.532	.003	.002	3	2
BRCA	PLEKHF1 →	+1.132	+0.563	.001	.006	3	2
UCEC	CBY1 →	+0.964	+0.686	.002	.003	3	2
UCEC	RAPGEFL1 →	+1.661	+0.863	.003	.006	3	2
UCEC	CKB →	+1.514	+0.865	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,442 associations by consensus.

ZNF275 vs PIGF — LUAD

Explore this scatter interactively →