ZNF275

Across TCGA cell cohorts, ZNF275 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,102 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF275-associated GO terms across cancer lineages are Positive regulation of telomerase RNA localization to Cajal body, Negative regulation of myoblast fusion, and Regulation of organelle assembly. Each is linked with ZNF275 in more than 13 cancer types. Because this analysis shows association rather than direction, both ZNF275-to-partner and partner-to-ZNF275 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of telomerase RNA localization to Cajal body grouped by ZNF275-low versus ZNF275-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF275→partner) and Y-score (partner→ZNF275) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of telomerase RNA localization to Cajal body →	+0.125	+1.080	<.001	.002	3	14
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.144	+0.856	.002	.002	3	13
BONE	Regulation of organelle assembly →	+0.045	+1.169	<.001	.002	3	13
UPPER_AERODIGESTIVE_TRACT	U2-type prespliceosome assembly →	+0.116	+0.916	.003	<.001	2	14
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.139	+0.885	.002	.001	3	13
BONE	Negative regulation of transcription initiation by RNA polymerase II →	+0.127	+1.052	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,102 associations by consensus.

Positive regulation of telomerase RNA localization to Cajal body by ZNF275 expression — BONE

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